3BM4

Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with magnesium and AMPcpr

Summary for 3BM4

• Entry DOI: 10.2210/pdb3bm4/pdb
• Related: 2DSB 2DSC 2DSD
• Descriptor: ADP-sugar pyrophosphatase, MAGNESIUM ION, ALPHA-BETA METHYLENE ADP-RIBOSE, ... (4 entities in total)
• Functional Keywords: nudix domain, adpr, adp-ribose pyrophosphatase, nudt5, molecular mechanism, substrate specificity, hydrolase, magnesium, phosphoprotein, polymorphism
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus : Q9UKK9
• Total number of polymer chains: 2
• Total formula weight: 47759.04

Authors

Zha, M.,Guo, Q.,Zhang, Y.,Zhong, C.,Ou, Y.,Ding, J. (deposition date: 2007-12-12, release date: 2008-05-20, Last modification date: 2023-11-01)

• Primary citation: Zha, M.,Guo, Q.,Zhang, Y.,Yu, B.,Ou, Y.,Zhong, C.,Ding, J.; Molecular Mechanism of ADP-Ribose Hydrolysis By Human NUDT5 From Structural and Kinetic Studies; J.Mol.Biol., 379:568-578, 2008; PubMed: 18462755; DOI: 10.1016/j.jmb.2008.04.006

Experimental method

X-RAY DIFFRACTION (2 Å)