3BG3
Crystal Structure of Human Pyruvate Carboxylase (missing the biotin carboxylase domain at the N-terminus)
Summary for 3BG3
Entry DOI | 10.2210/pdb3bg3/pdb |
Related | 1rqh 3BG5 3BG9 |
Descriptor | Pyruvate carboxylase, mitochondrial, MANGANESE (II) ION, PYRUVIC ACID, ... (4 entities in total) |
Functional Keywords | tim barrel, atp-binding, biotin, disease mutation, gluconeogenesis, ligase, lipid synthesis, manganese, mitochondrion, multifunctional enzyme, nucleotide-binding, phosphoprotein, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P11498 |
Total number of polymer chains | 4 |
Total formula weight | 316157.56 |
Authors | |
Primary citation | Xiang, S.,Tong, L. Crystal structures of human and Staphylococcus aureus pyruvate carboxylase and molecular insights into the carboxyltransfer reaction. Nat.Struct.Mol.Biol., 15:295-302, 2008 Cited by PubMed: 18297087DOI: 10.1038/nsmb.1393 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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