3AR5

Calcium pump crystal structure with bound TNP-AMP and TG

Summary for 3AR5

• Entry DOI: 10.2210/pdb3ar5/pdb
• Related: 2AGV 2DQS 2ZBD 3AR2 3AR3 3AR4 3AR6 3AR7 3AR8 3AR9
• Descriptor: Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, SODIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4ALPHA, 6BETA, 6ABETA, 7BETA, 8ALPHA(Z), 9BALPHA]]-6-(ACETYLOXY)-2,3,-3A,4,5,6,6A,7,8,9B-DECAHYDRO-3,3A-DIHYDROXY-3,6,9-TRIMETHYL-8-[(2-METHYL-1-OXO-2-BUTENYL)OX Y]-2-OXO-4-(1-OXOBUTOXY)-AZULENO[4,5-B]FURAN-7-YL ESTER, ... (6 entities in total)
• Functional Keywords: p-type atpase, hydrolase, calcium transport, calcium binding, atp binding, endoplasmic reticulum, sarcoplasmic reticulum, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Oryctolagus cuniculus (rabbits)
• Cellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein: P04191
• Total number of polymer chains: 1
• Total formula weight: 113062.79

Authors

Toyoshima, C.,Yonekura, S.,Tsueda, J.,Iwasawa, S. (deposition date: 2010-11-24, release date: 2011-02-02, Last modification date: 2024-04-03)

• Primary citation: Toyoshima, C.,Yonekura, S.,Tsueda, J.,Iwasawa, S.; Trinitrophenyl derivatives bind differently from parent adenine nucleotides to Ca2+-ATPase in the absence of Ca2+; Proc.Natl.Acad.Sci.USA, 108:1833-1838, 2011; PubMed: 21239683; DOI: 10.1073/pnas.1017659108

Experimental method

X-RAY DIFFRACTION (2.2 Å)