3X1O
Crystal structure of the ROQ domain of human Roquin
Summary for 3X1O
| Entry DOI | 10.2210/pdb3x1o/pdb |
| Related | 4TXA |
| Descriptor | Roquin-1, IODIDE ION (3 entities in total) |
| Functional Keywords | winged-helix motif, rna, cytosol, rna binding protein |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, P-body : Q5TC82 |
| Total number of polymer chains | 2 |
| Total formula weight | 50211.59 |
| Authors | Ose, T.,Verma, A.,Cockburn, J.B.,Berrow, N.S.,Alderton, D.,Stuart, D.,Owens, R.J.,Jones, E.Y. (deposition date: 2014-11-26, release date: 2015-03-11, Last modification date: 2024-03-20) |
| Primary citation | Srivastava, M.,Duan, G.,Kershaw, N.J.,Athanasopoulos, V.,Yeo, J.H.,Ose, T.,Hu, D.,Brown, S.H.J.,Jergic, S.,Patel, H.R.,Pratama, A.,Richards, S.,Verma, A.,Jones, E.Y.,Heissmeyer, V.,Preiss, T.,Dixon, N.E.,Chong, M.M.W.,Babon, J.J.,Vinuesa, C.G. Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis Nat Commun, 6:6253-6253, 2015 Cited by PubMed: 25697406DOI: 10.1038/ncomms7253 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.201 Å) |
Structure validation
Download full validation report
