3UPY

Crystal structure of the Brucella abortus enzyme catalyzing the first committed step of the methylerythritol 4-phosphate pathway.

Summary for 3UPY

• Entry DOI: 10.2210/pdb3upy/pdb
• Related: 3UPL
• Descriptor: Oxidoreductase, MAGNESIUM ION, 3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID, ... (4 entities in total)
• Functional Keywords: rossmann fold, oxidoreductase, nadph binding
• Biological source: Brucella melitensis biovar Abortus 2308
• Total number of polymer chains: 2
• Total formula weight: 95560.83

Authors

Calisto, B.M.,Perez-Gil, J.,Fita, I.,Rodriguez-Concepcion, M. (deposition date: 2011-11-18, release date: 2012-03-28, Last modification date: 2023-09-13)

• Primary citation: Perez-Gil, J.,Calisto, B.M.,Behrendt, C.,Kurz, T.,Fita, I.,Rodriguez-Concepcion, M.; Crystal structure of Brucella abortus deoxyxylulose-5-phosphate reductoisomerase-like (DRL) enzyme involved in isoprenoid biosynthesis.; J.Biol.Chem., 287:15803-15809, 2012; PubMed: 22442144; DOI: 10.1074/jbc.M112.354811

Experimental method

X-RAY DIFFRACTION (1.8 Å)