3UN7

Crystal structure of PBPA from MYCOBACTERIUM TUBERCULOSIS

Summary for 3UN7

• Entry DOI: 10.2210/pdb3un7/pdb
• Related: 3LO7
• Descriptor: Penicillin-binding protein A (2 entities in total)
• Functional Keywords: transpeptidase, penicillin-binding protein, peptidoglycan, beta-lactam, transferase
• Biological source: Mycobacterium tuberculosis
• Cellular location: Cell membrane; Single-pass type II membrane protein (Probable): P71586
• Total number of polymer chains: 2
• Total formula weight: 96928.98

Authors

Fedarovich, A.,Davies, C. (deposition date: 2011-11-15, release date: 2012-10-24, Last modification date: 2023-09-13)

• Primary citation: Fedarovich, A.,Nicholas, R.A.,Davies, C.; The role of the beta5-alpha11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis; J.Mol.Biol., 418:316-330, 2012; PubMed: 22365933; DOI: 10.1016/j.jmb.2012.02.021

Experimental method

X-RAY DIFFRACTION (2 Å)