3U05

Crystal structure of DB1804-D(CGCGAATTCGCG)2 complex

Summary for 3U05

• Entry DOI: 10.2210/pdb3u05/pdb
• Related: 3U08
• Descriptor: 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G)-3', MAGNESIUM ION, 6-(1,4,5,6-tetrahydropyrimidin-2-yl)-2-[4'-(1,4,5,6-tetrahydropyrimidin-2-yl)biphenyl-4-yl]-1H-indole, ... (4 entities in total)
• Functional Keywords: a2t2, dickerson and drew dodecamer, double helix, dna minor groove-ligand complex, dna minor groove binder, db1804, mg2+, dna
• Total number of polymer chains: 2
• Total formula weight: 7784.64

Authors

Wei, D.G.,Neidle, S. (deposition date: 2011-09-28, release date: 2012-09-12, Last modification date: 2024-02-28)

• Primary citation: Wei, D.,Wilson, W.D.,Neidle, S.; Small-molecule binding to the DNA minor groove is mediated by a conserved water cluster.; J.Am.Chem.Soc., 135:1369-1377, 2013; PubMed: 23276263; DOI: 10.1021/ja308952y

Experimental method

X-RAY DIFFRACTION (1.27 Å)