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3TMH

Crystal structure of dual-specific A-kinase anchoring protein 2 in complex with cAMP-dependent protein kinase A type II alpha and PDZK1

Summary for 3TMH
Entry DOI10.2210/pdb3tmh/pdb
DescriptorNa(+)/H(+) exchange regulatory cofactor NHE-RF3, cAMP-dependent protein kinase type II-alpha regulatory subunit, A-kinase anchor protein 10, mitochondrial, ... (4 entities in total)
Functional Keywordsalpha helical bundle, pdz fold, anchoring protein, pka, pdz proteins, membrane, transport protein-signaling protein complex, transport protein/signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm (By similarity): Q5T2W1 P12368
Mitochondrion: O43572
Total number of polymer chains10
Total formula weight65262.08
Authors
Sarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S. (deposition date: 2011-08-31, release date: 2012-09-05, Last modification date: 2024-02-28)
Primary citationSarma, G.N.,Phan, R.H.,Sankaran, B.,Taylor, S.S.
Differential mode of D-AKAP2 to PKA isoforms: Insights from D-AKAP2 PKA RII PDZK1 ternary complex structure
To be Published,
Experimental method
X-RAY DIFFRACTION (3.8 Å)
Structure validation

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