3SY2

Crystal structure of the Salmonella E3 ubiquitin ligase SopA in complex with the human E2 UbcH7

Summary for 3SY2

Entry DOI	10.2210/pdb3sy2/pdb
Descriptor	E3 ubiquitin-protein ligase SopA, Ubiquitin-conjugating enzyme E2 L3, SULFATE ION, ... (4 entities in total)
Functional Keywords	pentapeptide, hect domain, hect e3, hect e3 ubiquitin ligase, e2 ubiquitin conjugating enzyme, ubiquitin, protein-protein complex, effector protein, ubiquitin transfer, ubiquitination, ligase-signaling protein complex, ligase/signaling protein
Biological source	Salmonella enterica subsp. enterica serovar Typhimurium More
Cellular location	Secreted: Q8ZNR3 Nucleus: P68036
Total number of polymer chains	4
Total formula weight	174633.95
Authors	Diao, J.,Lin, D.Y.,Chen, J. (deposition date: 2011-07-15, release date: 2012-01-25, Last modification date: 2023-09-13)
Primary citation	Lin, D.Y.,Diao, J.,Chen, J. Crystal structures of two bacterial HECT-like E3 ligases in complex with a human E2 reveal atomic details of pathogen-host interactions. Proc.Natl.Acad.Sci.USA, 109:1925-1930, 2012 Cited by PubMed: 22308380 DOI: 10.1073/pnas.1115025109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.27 Å)

Structure validation