3QUM
Crystal structure of human prostate specific antigen (PSA) in Fab sandwich with a high affinity and a PCa selective antibody
Summary for 3QUM
Entry DOI | 10.2210/pdb3qum/pdb |
Related | 2ZCH 2ZCK 2ZCL |
Related PRD ID | PRD_900084 |
Descriptor | Prostate-specific antigen, Fab 5D3D11 Light Chain, Fab 5D3D11 Heavy Chain, ... (9 entities in total) |
Functional Keywords | kallikrein fold, prostate-specific antigen, serine protease, negative regulation of angiogenesis, natural post-transductional modification, n-linked and o-linked glycosylation, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted: P07288 |
Total number of polymer chains | 10 |
Total formula weight | 249837.88 |
Authors | Stura, E.A.,Muller, B.H.,Michel, S.,Ducancel, F. (deposition date: 2011-02-24, release date: 2011-11-09, Last modification date: 2023-09-13) |
Primary citation | Stura, E.A.,Muller, B.H.,Bossus, M.,Michel, S.,Jolivet-Reynaud, C.,Ducancel, F. Crystal structure of human prostate-specific antigen in a sandwich antibody complex. J.Mol.Biol., 414:530-544, 2011 Cited by PubMed: 22037582DOI: 10.1016/j.jmb.2011.10.007 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.2 Å) |
Structure validation
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