3NID

The Closed Headpiece of Integrin alphaIIB beta3 and its Complex with an alpahIIB beta3 -Specific Antagonist That Does Not Induce Opening

Summary for 3NID

• Entry DOI: 10.2210/pdb3nid/pdb
• Related: 2VDR 3NID 3NIF 3NIG
• Descriptor: Integrin alpha-IIb, SULFATE ION, MAGNESIUM ION, ... (13 entities in total)
• Functional Keywords: integrin, headpiece, alphaiib, beta3, cell adhesion-blood clotting complex, cell adhesion/blood clotting
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 302255.43

Authors

Zhu, J.H.,Zhu, J.Q.,Springer, T.A. (deposition date: 2010-06-15, release date: 2010-12-22, Last modification date: 2023-09-06)

• Primary citation: Zhu, J.H.,Zhu, J.Q.,Negri, A.,Provasi, D.,Filizola, M.,Coller, B.S.,Springer, T.A.; Closed headpiece of integrin {alpha}IIb{beta}3 and its complex with an {alpha}IIb{beta}3-specific antagonist that does not induce opening.; Blood, 116:5050-5059, 2010; PubMed: 20679525; DOI: 10.1182/blood-2010-04-281154

Experimental method

X-RAY DIFFRACTION (2.3 Å)