3MPA

Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding

Summary for 3MPA

• Entry DOI: 10.2210/pdb3mpa/pdb
• Related: 3MGY 3MH0 3MH1 3MH2 3MH3
• Descriptor: Mitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, octyl beta-D-glucopyranoside, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 41954.96

Authors

Namboodiri, H.V.,Karpusas, M.,Bukhtiyarova, M.,Springman, E.B. (deposition date: 2010-04-26, release date: 2010-09-15, Last modification date: 2023-09-06)

• Primary citation: Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J.; Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding; TO BE PUBLISHED,

Experimental method

X-RAY DIFFRACTION (2.1 Å)