3MPA
Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding
Summary for 3MPA
Entry DOI | 10.2210/pdb3mpa/pdb |
Related | 3MGY 3MH0 3MH1 3MH2 3MH3 |
Descriptor | Mitogen-activated protein kinase 14, 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, octyl beta-D-glucopyranoside, ... (4 entities in total) |
Functional Keywords | transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 41954.96 |
Authors | Namboodiri, H.V.,Karpusas, M.,Bukhtiyarova, M.,Springman, E.B. (deposition date: 2010-04-26, release date: 2010-09-15, Last modification date: 2023-09-06) |
Primary citation | Namboodiri, H.V.,Springman, E.B.,Karpusas, M.,Bukhtiyarova, M.,Ramcharan, J. Conformational plasticity of p38 MAP kinase DFG motif mutants in response to inhibitor binding TO BE PUBLISHED, |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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