3JBT

Atomic structure of the Apaf-1 apoptosome

Summary for 3JBT

• Entry DOI: 10.2210/pdb3jbt/pdb
• EMDB information: 6480
• Descriptor: Apoptotic protease-activating factor 1, Cytochrome c, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, ... (5 entities in total)
• Functional Keywords: apoptosome, cryo-em structure, apoptosis, apaf-1
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 14
• Total formula weight: 1096452.78

Authors

Zhou, M.,Li, Y.,Hu, Q.,Bai, X.,Huang, W.,Yan, C.,Scheres, S.H.W.,Shi, Y. (deposition date: 2015-10-15, release date: 2015-11-18, Last modification date: 2019-12-18)

• Primary citation: Zhou, M.,Li, Y.,Hu, Q.,Bai, X.C.,Huang, W.,Yan, C.,Scheres, S.H.W.,Shi, Y.; Atomic structure of the apoptosome: mechanism of cytochrome c- and dATP-mediated activation of Apaf-1; Genes Dev., 29:2349-2361, 2015; PubMed: 26543158; DOI: 10.1101/gad.272278.115

Experimental method

ELECTRON MICROSCOPY (3.8 Å)