3IOL

Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor

3IOL の概要

• エントリーDOI: 10.2210/pdb3iol/pdb
• 関連するPDBエントリー: 3C59 3C5T
• 分子名称: Glucagon-like peptide 1 receptor, Glucagon, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside, ... (4 entities in total)
• 機能のキーワード: receptor-ligand complex, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, membrane, receptor, transducer, transmembrane, amidation, cleavage on pair of basic residues, hormone, secreted, signaling protein-signaling protein complex, signaling protein/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane ; Multi- pass membrane protein : P43220; Secreted: P01275
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 18597.64

構造登録者

Reedtz-Runge, S. (登録日: 2009-08-14, 公開日: 2009-10-27, 最終更新日: 2023-11-01)

• 主引用文献: Underwood, C.R.,Garibay, P.,Knudsen, L.B.,Hastrup, S.,Peters, G.H.,Rudolph, R.,Reedtz-Runge, S.; Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor; J.Biol.Chem., 285:723-730, 2010; PubMed: 19861722; DOI: 10.1074/jbc.M109.033829

実験手法

X-RAY DIFFRACTION (2.1 Å)