3I3Z

Human insulin

Summary for 3I3Z

• Entry DOI: 10.2210/pdb3i3z/pdb
• Related: 3I40
• Descriptor: Insulin A chain, Insulin B chain (3 entities in total)
• Functional Keywords: insulin, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 2
• Total formula weight: 5787.63

Authors

Timofeev, V.I.,Bezuglov, V.V.,Miroshnikov, K.A.,Cuprov-Netochin, R.N.,Samigina, V.R.,Kuranova, I.P. (deposition date: 2009-07-01, release date: 2010-01-05, Last modification date: 2011-07-13)

• Primary citation: Timofeev, V.I.,Chuprov-Netochin, R.N.,Samigina, V.R.,Bezuglov, V.V.,Miroshnikov, K.A.,Kuranova, I.P.; X-ray investigation of gene-engineered human insulin crystallized from a solution containing polysialic acid.; Acta Crystallogr.,Sect.F, 66:259-263, 2010; PubMed: 20208155; DOI: 10.1107/S1744309110000461

Experimental method

X-RAY DIFFRACTION (1.6 Å)