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3HMO

Crystal structure of human Mps1 catalytic domain in complex with the inhibitor staurosporine

Summary for 3HMO
Entry DOI10.2210/pdb3hmo/pdb
Related2ZMC 2ZMD 3HMN 3HMP
DescriptorDual specificity protein kinase TTK, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, STAUROSPORINE, ... (6 entities in total)
Functional Keywordsmps1, ttk, stu, staurosporine, kinase, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, tyrosine-protein kinase, transferase
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total formula weight40412.02
Authors
Chu, M.L.H.,Chavas, L.M.G.,Williams, D.H.,Tabernero, L.,Eyers, P.A. (deposition date: 2009-05-29, release date: 2010-02-02, Last modification date: 2023-09-06)
Primary citationChu, M.L.,Lang, Z.,Chavas, L.M.,Neres, J.,Fedorova, O.S.,Tabernero, L.,Cherry, M.,Williams, D.H.,Douglas, K.T.,Eyers, P.A.
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
Biochemistry, 49:1689-1701, 2010
Cited by
PubMed: 20099905
DOI: 10.1021/bi901970c
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

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数据于2024-03-13公开中

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