3H0T

Hepcidin-Fab complex

Summary for 3H0T

• Entry DOI: 10.2210/pdb3h0t/pdb
• Descriptor: Fab fragment, Light chain, Fab fragment, Heavy chain, Hepcidin, ... (4 entities in total)
• Functional Keywords: peptide-fab complex, antibiotic, antimicrobial, cleavage on pair of basic residues, disease mutation, disulfide bond, fungicide, hormone, secreted, immune system-antimicrobial protein complex, immune system/antimicrobial protein
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P81172
• Total number of polymer chains: 3
• Total formula weight: 51436.13

Authors

Syed, R.,Li, V. (deposition date: 2009-04-10, release date: 2009-06-23, Last modification date: 2023-09-06)

• Primary citation: Jordan, J.B.,Poppe, L.,Haniu, M.,Arvedson, T.,Syed, R.,Li, V.,Kohno, H.,Kim, H.,Schnier, P.D.,Harvey, T.S.,Miranda, L.P.,Cheetham, J.,Sasu, B.J.; Hepcidin revisited, disulfide connectivity, dynamics, and structure.; J.Biol.Chem., 284:24155-24167, 2009; PubMed: 19553669; DOI: 10.1074/jbc.M109.017764

Experimental method

X-RAY DIFFRACTION (1.89 Å)