3F92

Crystal structure of ubiquitin-conjugating enzyme E2-25kDa (Huntington Interacting Protein 2) M172A mutant crystallized at pH 8.5

Summary for 3F92

Entry DOI	10.2210/pdb3f92/pdb
Related	1JBB 1YLA 3E46
Descriptor	Ubiquitin-conjugating enzyme E2 K, TETRAETHYLENE GLYCOL, BETA-MERCAPTOETHANOL, ... (6 entities in total)
Functional Keywords	ubiquitin-conjugating, huntington interacting, e2-25k, ligase, ubiquitin-conjugating enzyme e2 k, e2(25k), ubiquitin-protein ligase, ubiquitin carrier protein, huntington-interacting protein 2, hip-2, alternative splicing, cytoplasm, ubl conjugation, ubl conjugation pathway
Biological source	Homo sapiens (Human)
Cellular location	Cytoplasm : P61086
Total number of polymer chains	1
Total formula weight	28834.65
Authors	Wilson, R.C.,Hughes, R.C.,Flatt, J.W.,Meehan, E.J.,Ng, J.D.,Twigg, P.D. (deposition date: 2008-11-13, release date: 2008-11-25, Last modification date: 2023-09-06)
Primary citation	Wilson, R.C.,Hughes, R.C.,Flatt, J.W.,Meehan, E.J.,Ng, J.D.,Twigg, P.D. Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2). Acta Crystallogr.,Sect.F, 65:440-444, 2009 Cited by PubMed: 19407372 DOI: 10.1107/S1744309109011117 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.23 Å)

Structure validation