3EWO

IBV Nsp3 ADRP domain

3EWO の概要

• エントリーDOI: 10.2210/pdb3ewo/pdb
• 関連するPDBエントリー: 3EWP 3EWQ 3EWR
• 分子名称: Non-structural protein 3 (2 entities in total)
• 機能のキーワード: globular like, cytoplasm, hydrolase, membrane, metal-binding, protease, ribosomal frameshifting, rna-binding, thiol protease, transmembrane, zinc, zinc-finger
• 由来する生物種: Avian infectious bronchitis virus (IBV)
• 細胞内の位置: Non-structural protein 3: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 4: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 6: Host membrane; Multi-pass membrane protein (Potential). Non-structural protein 7: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 8: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 9: Host cytoplasm, host perinuclear region (By similarity). Non-structural protein 10: Host cytoplasm, host perinuclear region (By similarity): P0C6V5
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 38408.58

構造登録者

Xu, Y.,Cong, L.,Chen, C.,Wei, L.,Zhao, Q.,Xu, X.,Ma, Y.,Bartlam, M.,Rao, Z. (登録日: 2008-10-16, 公開日: 2009-01-13, 最終更新日: 2023-12-27)

• 主引用文献: Xu, Y.,Cong, L.,Chen, C.,Wei, L.,Zhao, Q.,Xu, X.,Ma, Y.,Bartlam, M.,Rao, Z.; Crystal structures of two coronavirus ADP-ribose-1''-monophosphatases and their complexes with ADP-Ribose: a systematic structural analysis of the viral ADRP domain.; J.Virol., 83:1083-1092, 2009; PubMed: 18987156; DOI: 10.1128/JVI.01862-08

実験手法

X-RAY DIFFRACTION (1.8 Å)