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3DZI

Crystal structure of human CD38 extracellular domain, ribose-5'-phosphate intermediate/GTP complex

Summary for 3DZI
Entry DOI10.2210/pdb3dzi/pdb
Related3DZF 3DZG 3DZH 3DZJ 3DZK
DescriptorADP-ribosyl cyclase 1, 2-amino-9-{5-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]oxy}phosphoryl]-beta-D-ribofuranosyl}-9H-purin-6-yl 5-O-phosphono-beta-D-ribofuranoside, ANY 5'-MONOPHOSPHATE NUCLEOTIDE, ... (5 entities in total)
Functional Keywordsnoncovalent intermediate, gtp complex, r5p-gtp adduct, beta sheets, alpha bundle, alternative splicing, diabetes mellitus, glycoprotein, hydrolase, membrane, nad, polymorphism, receptor, signal-anchor, transmembrane
Biological sourceHomo sapiens
Cellular locationMembrane; Single-pass type II membrane protein: P28907
Total number of polymer chains2
Total formula weight62233.35
Authors
Liu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q. (deposition date: 2008-07-29, release date: 2008-11-04, Last modification date: 2023-08-30)
Primary citationLiu, Q.,Kriksunov, I.A.,Jiang, H.,Graeff, R.,Lin, H.,Lee, H.C.,Hao, Q.
Covalent and Noncovalent Intermediates of an NAD Utilizing Enzyme, Human CD38.
Chem.Biol., 15:1068-1078, 2008
Cited by
PubMed: 18940667
DOI: 10.1016/j.chembiol.2008.08.007
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.73 Å)
Structure validation

217705

건을2024-03-27부터공개중

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