3DUH
Structure of Interleukin-23
Summary for 3DUH
Entry DOI | 10.2210/pdb3duh/pdb |
Descriptor | Interleukin-12 subunit beta, Interleukin-23 subunit alpha, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | four-helix bundle cytokine, ig domain, cytokine, glycoprotein, immunoglobulin domain, secreted, antiviral defense, immune response, inflammatory response, innate immunity, tissue remodeling, immune system, immune system-cytokine complex, immune system/cytokine |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 111340.92 |
Authors | Lupardus, P.J.,Garcia, K.C. (deposition date: 2008-07-17, release date: 2008-08-19, Last modification date: 2023-08-30) |
Primary citation | Lupardus, P.J.,Garcia, K.C. The structure of interleukin-23 reveals the molecular basis of p40 subunit sharing with interleukin-12. J.Mol.Biol., 382:931-941, 2008 Cited by PubMed: 18680750DOI: 10.1016/j.jmb.2008.07.051 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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