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3CR6

Crystal Structure of the R132K:R111L:A32E Mutant of Cellular Retinoic Acid Binding Protein Type II Complexed with C15-aldehyde (a retinal analog) at 1.22 Angstrom resolution.

Summary for 3CR6
Entry DOI10.2210/pdb3cr6/pdb
DescriptorCellular retinoic acid-binding protein 2, 1,3,3-trimethyl-2-[(1E,3E)-3-methylpenta-1,3-dien-1-yl]cyclohexene (3 entities in total)
Functional Keywordscrabpii, retinal, schiff base, protonated schiff base, psb, c15-aldehyde, retinoic acid, retinoid, nucleus, retinol-binding, transport, vitamin a, transport protein
Biological sourceHomo sapiens (Human)
Cellular locationCytoplasm: P29373
Total number of polymer chains1
Total formula weight15772.14
Authors
Jia, X.,Geiger, J.H. (deposition date: 2008-04-04, release date: 2009-03-17, Last modification date: 2023-08-30)
Primary citationJia, X.,Lee, K.S.,Vasileiou, C.,Borhan, B.,Geiger, J.H.
Two distinctive orientations of binding determined by a single mutation in the CRABPII mutant-C15-aldehyde complexes
To be Published,
Experimental method
X-RAY DIFFRACTION (1.22 Å)
Structure validation

218500

數據於2024-04-17公開中

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