3AAF

Structure of WRN RQC domain bound to double-stranded DNA

Summary for 3AAF

• Entry DOI: 10.2210/pdb3aaf/pdb
• Descriptor: Werner syndrome ATP-dependent helicase, DNA (5'-D(*AP*CP*CP*CP*TP*AP*AP*TP*TP*AP*GP*GP*GP*T)-3'), ACETATE ION, ... (4 entities in total)
• Functional Keywords: helix-turn-helix, winged-helix, protein-dna complex, dna-binding, helicase, dna binding protein-dna complex, dna binding protein/dna
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus, nucleolus : Q14191
• Total number of polymer chains: 4
• Total formula weight: 39380.79

Authors

Kitano, K.,Hakoshima, T. (deposition date: 2009-11-16, release date: 2010-02-16, Last modification date: 2024-03-13)

• Primary citation: Kitano, K.,Kim, S.Y.,Hakoshima, T.; Structural basis for DNA strand separation by the unconventional winged-helix domain of RecQ helicase WRN; Structure, 18:177-187, 2010; PubMed: 20159463; DOI: 10.1016/j.str.2009.12.011

Experimental method

X-RAY DIFFRACTION (1.9 Å)