2ZXG

Aminopeptidase N complexed with the aminophosphinic inhibitor of PL250, a transition state analogue

2ZXG の概要

• エントリーDOI: 10.2210/pdb2zxg/pdb
• 関連するPDBエントリー: 2DQ6 2DQM
• 分子名称: Aminopeptidase N, ZINC ION, N-{(2S)-3-[(1R)-1-aminoethyl](hydroxy)phosphoryl-2-benzylpropanoyl}-L-phenylalanine, ... (6 entities in total)
• 機能のキーワード: clan ma, family m1, zinc peptidase, inhibitor complex, transition state, aminopeptidase, cell inner membrane, cell membrane, hydrolase, membrane, metal-binding, metalloprotease, protease
• 由来する生物種: Escherichia coli K-12
• 細胞内の位置: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 100253.19

構造登録者

Nakajima, Y.,Ito, K.,Yoshimoto, T. (登録日: 2008-12-24, 公開日: 2009-08-25, 最終更新日: 2023-11-01)

• 主引用文献: Fournie-Zaluski, M.C.,Poras, H.,Roques, B.P.,Nakajima, Y.,Ito, K.,Yoshimoto, T.; Structure of aminopeptidase N from Escherichia coli complexed with the transition-state analogue aminophosphinic inhibitor PL250; Acta Crystallogr.,Sect.D, 65:814-822, 2009; PubMed: 19622865; DOI: 10.1107/S090744490901779X

実験手法

X-RAY DIFFRACTION (1.55 Å)