2ZWF

Crystal structure of the copper-bound tyrosinase in complex with a caddie protein from streptomyces castaneoglobisporus obtained by soaking the deoxy-form crystal in dioxygen-saturated solution for 80 minutes

Summary for 2ZWF

• Entry DOI: 10.2210/pdb2zwf/pdb
• Related: 1wx2 1wxc 2zmx 2zmy 2zmz 2zwc 2zwd 2zwe 2zwg
• Descriptor: Tyrosinase, MelC, COPPER (II) ION, ... (5 entities in total)
• Functional Keywords: tyrosinase, binary complex, type-3 copper, dioxygen, copper transfer, oxidoreductase-metal transport complex, oxidoreductase/metal transport
• Biological source: Streptomyces castaneoglobisporus; More
• Total number of polymer chains: 2
• Total formula weight: 46873.58

Authors

Matoba, Y.,Sugiyama, M. (deposition date: 2008-12-03, release date: 2009-12-15, Last modification date: 2023-11-01)

• Primary citation: Matoba, Y.,Yoshitsu, H.,Jeon, H.J.,Oda, K.,Noda, M.,Kumagai, T.,Sugiyama, M.; Crystallographic evidence of drastic movement of a copper ion toward the substrate tyrosine for starting hydroxylation reaction of tyrosinase; To be Published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)