2ZVO

NEMO CoZi domain in complex with diubiquitin in C2 space group

Summary for 2ZVO

Entry DOI	10.2210/pdb2zvo/pdb
Related	2ZVN 3F89
Descriptor	UBC protein, NF-kappa-B essential modulator (3 entities in total)
Functional Keywords	nf-kb signaling, ubiquitin binding, coiled coil, cytoplasm, metal-binding, nucleus, phosphoprotein, transcription, transcription regulation, ubl conjugation, zinc, zinc-finger, transcription-signaling protein complex, transcription/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm : O88522
Total number of polymer chains	4
Total formula weight	55911.87
Authors	Rahighi, S.,Ikeda, F.,Kawasaki, M.,Akutsu, M.,Suzuki, N.,Kato, R.,Kensche, T.,Uejima, T.,Bloor, S.,Komander, D.,Randow, F.,Wakatsuki, S.,Dikic, I. (deposition date: 2008-11-12, release date: 2009-03-24, Last modification date: 2021-11-10)
Primary citation	Rahighi, S.,Ikeda, F.,Kawasaki, M.,Akutsu, M.,Suzuki, N.,Kato, R.,Kensche, T.,Uejima, T.,Bloor, S.,Komander, D.,Randow, F.,Wakatsuki, S.,Dikic, I. Specific recognition of linear ubiquitin chains by NEMO is important for NF-kappaB activation Cell(Cambridge,Mass.), 136:1098-1109, 2009 Cited by PubMed: 19303852 DOI: 10.1016/j.cell.2009.03.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation