2ZKH
Human thrombopoietin neutralizing antibody TN1 FAB
Summary for 2ZKH
| Entry DOI | 10.2210/pdb2zkh/pdb |
| Descriptor | Monoclonal TN1 FAB light chain, Monoclonal TN1 FAB heavy chain (3 entities in total) |
| Functional Keywords | thrombopoietin, fab fragment(antibody), immune system |
| Biological source | Homo sapiens (human) More |
| Total number of polymer chains | 2 |
| Total formula weight | 46727.02 |
| Authors | Arai, S.,Tamada, T.,Honjo, E.,Maeda, Y.,Kuroki, R. (deposition date: 2008-03-21, release date: 2009-03-24, Last modification date: 2023-11-01) |
| Primary citation | Arai, S.,Shibazaki, C.,Adachi, M.,Honjo, E.,Tamada, T.,Maeda, Y.,Tahara, T.,Kato, T.,Miyazaki, H.,Blaber, M.,Kuroki, R. An insight into the thermodynamic characteristics of human thrombopoietin complexation with TN1 antibody. Protein Sci., 25:1786-1796, 2016 Cited by PubMed: 27419667DOI: 10.1002/pro.2985 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.04 Å) |
Structure validation
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