2ZHX

Crystal structure of Uracil-DNA Glycosylase from Mycobacterium tuberculosis in complex with a proteinaceous inhibitor

Summary for 2ZHX

Entry DOI	10.2210/pdb2zhx/pdb
Descriptor	Uracil-DNA glycosylase, Uracil-DNA glycosylase inhibitor (3 entities in total)
Functional Keywords	dna repair, ung-ugi complex, ung-dna interactions, dna damage, glycosidase, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Mycobacterium tuberculosis H37Rv More
Total number of polymer chains	14
Total formula weight	247073.52
Authors	Kaushal, P.S.,Talawar, R.K.,Krishna, P.D.V.,Varshney, U.,Vijayan, M. (deposition date: 2008-02-11, release date: 2008-05-20, Last modification date: 2023-11-01)
Primary citation	Kaushal, P.S.,Talawar, R.K.,Krishna, P.D.V.,Varshney, U.,Vijayan, M. Unique features of the structure and interactions of mycobacterial uracil-DNA glycosylase: structure of a complex of the Mycobacterium tuberculosis enzyme in comparison with those from other sources Acta Crystallogr.,Sect.D, 64:551-560, 2008 Cited by PubMed: 18453691 DOI: 10.1107/S090744490800512X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation