Crystal structure of CERT START domain in complex with C10-diacylglycerol

Summary for 2Z9Y

Related2E3M 2E3N 2E3O 2E3P 2E3Q 2E3R 2E3S 2Z9Z
DescriptorLipid-transfer protein CERT, (2S)-3-hydroxypropane-1,2-diyl didecanoate (3 entities in total)
Functional Keywordslipid transfer protein, cert, ceramide transfer, lipid transport
Biological sourceHomo sapiens (human)
Total number of polymer chains1
Total molecular weight29332.36
Kudo, N.,Kumagai, K.,Wakatsuki, S.,Nishijima, M.,Hanada, K.,Kato, R. (deposition date: 2007-09-26, release date: 2008-02-12, Last modification date: 2011-07-13)
Primary citation
Kudo, N.,Kumagai, K.,Tomishige, N.,Yamaji, T.,Wakatsuki, S.,Nishijima, M.,Hanada, K.,Kato, R.
Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide.
Proc.Natl.Acad.Sci.Usa, 105:488-493, 2008
PubMed: 18184806 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0709191105
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.269403.4%6.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution