2YHN

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

Summary for 2YHN

• Entry DOI: 10.2210/pdb2yhn/pdb
• Related: 2YHO
• Descriptor: E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION (2 entities in total)
• Functional Keywords: ligase, e2 ligase- e3 ligase complex, ring zinc-finger, ube2d1, ubl conjugation pathway
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Cytoplasm (Probable): Q8WY64
• Total number of polymer chains: 2
• Total formula weight: 17984.46

Authors

Fairall, L.,Goult, B.T.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W.R. (deposition date: 2011-05-04, release date: 2011-06-29, Last modification date: 2023-12-20)

• Primary citation: Zhang, L.,Fairall, L.,Goult, B.T.,Calkin, A.C.,Hong, C.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W.R.; The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.; Genes Dev., 25:1262-, 2011; PubMed: 21685362; DOI: 10.1101/GAD.2056211

Experimental method

X-RAY DIFFRACTION (3 Å)