Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

2XWA

Crystal Structure of Complement Factor D Mutant R202A

Summary for 2XWA
Entry DOI10.2210/pdb2xwa/pdb
Related1BIO 1DFP 1DIC 1DST 1DSU 1FDP 1HFD 2XW9 2XWB 2XWJ
DescriptorCOMPLEMENT FACTOR D, GLYCEROL (3 entities in total)
Functional Keywordsimmune system, hydrolase, serine protease, alternative pathway
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationSecreted: P00746
Total number of polymer chains2
Total formula weight48889.57
Authors
Forneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P. (deposition date: 2010-11-01, release date: 2011-01-12, Last modification date: 2023-12-20)
Primary citationForneris, F.,Ricklin, D.,Wu, J.,Tzekou, A.,Wallace, R.S.,Lambris, J.D.,Gros, P.
Structures of C3B in Complex with Factors B and D Give Insight Into Complement Convertase Formation.
Science, 330:1816-, 2010
Cited by
PubMed: 21205667
DOI: 10.1126/SCIENCE.1195821
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.8 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon