2XMB

G117H mutant of human butyrylcholinesterase in complex with sulfate

Summary for 2XMB

Entry DOI	10.2210/pdb2xmb/pdb
Related	1EHO 1EHQ 1KCJ 1P0I 1P0M 1P0P 1P0Q 1XLU 1XLV 1XLW 2J4C 2WID 2WIF 2WIG 2WIJ 2WIK 2WIL 2WSL 2XMC 2XMD 2XMG
Descriptor	CHOLINESTERASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (10 entities in total)
Functional Keywords	glycoprotein, hydrolase
Biological source	HOMO SAPIENS (HUMAN)
Total number of polymer chains	1
Total formula weight	62522.04
Authors	Nachon, F.,Carletti, E.,Wandhammer, M.,Nicolet, Y.,Schopfer, L.M.,Masson, P.,Lockridge, O. (deposition date: 2010-07-27, release date: 2010-12-01, Last modification date: 2023-12-20)
Primary citation	Nachon, F.,Carletti, E.,Wandhammer, M.,Nicolet, Y.,Schopfer, L.M.,Masson, P.,Lockridge, O. X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, a Nerve Agent Target Engineered Into a Catalytic Bioscavenge Biochem.J., 434:73-, 2011 Cited by PubMed: 21091433 DOI: 10.1042/BJ20101648 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation