2XKK

CRYSTAL STRUCTURE OF MOXIFLOXACIN, DNA, and A. BAUMANNII TOPO IV (PARE-PARC FUSION TRUNCATE)

Summary for 2XKK

Entry DOI	10.2210/pdb2xkk/pdb
Related	2XKJ
Descriptor	TOPOISOMERASE IV, DNA, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	isomerase-dna-antibiotic complex, type iia topoisomerase, quinolone, antibacterial agent, isomerase/dna/antibiotic
Biological source	ACINETOBACTER BAUMANNII More
Total number of polymer chains	4
Total formula weight	194147.10
Authors	Wohlkonig, A.,Chan, P.F.,Fosberry, A.P.,Homes, P.,Huang, J.,Kranz, M.,Leydon, V.R.,Miles, T.J.,Pearson, N.D.,Perera, R.L.,Shillings, A.J.,Gwynn, M.N.,Bax, B.D. (deposition date: 2010-07-08, release date: 2010-09-01, Last modification date: 2023-12-20)
Primary citation	Wohlkonig, A.,Chan, P.F.,Fosberry, A.P.,Homes, P.,Huang, J.,Kranz, M.,Leydon, V.R.,Miles, T.J.,Pearson, N.D.,Perera, R.L.,Shillings, A.J.,Gwynn, M.N.,Bax, B.D. Structural Basis of Quinolone Inhibition of Type Iia Topoisomerases and Target-Mediated Resistance Nat.Struct.Mol.Biol., 17:1152-, 2010 Cited by PubMed: 20802486 DOI: 10.1038/NSMB.1892 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.25 Å)

Structure validation