2XIQ

Crystal structure of human methylmalonyl-CoA mutase in complex with adenosylcobalamin and malonyl-CoA

2XIQ の概要

• エントリーDOI: 10.2210/pdb2xiq/pdb
• 関連するPDBエントリー: 2XIJ
• 分子名称: METHYLMALONYL-COA MUTASE, MITOCHONDRIAL, COBALAMIN, 5'-DEOXYADENOSINE, ... (5 entities in total)
• 機能のキーワード: organic aciduria, isomerase, metabolic disease, vitamin b12
• 由来する生物種: HOMO SAPIENS (HUMAN)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 174542.00

構造登録者

Yue, W.W.,Froese, D.S.,Kochan, G.,Chaikuad, A.,Krojer, T.,Muniz, J.,Ugochukwu, E.,Arrowsmith, C.,Weigelt, J.,Edwards, A.,Bountra, C.,Oppermann, U. (登録日: 2010-06-30, 公開日: 2010-09-29, 最終更新日: 2023-12-20)

• 主引用文献: Froese, D.S.,Kochan, G.,Muniz, J.,Wu, X.,Gileadi, C.,Ugochukwu, E.,Krysztofinska, E.,Gravel, R.A.,Oppermann, U.,Yue, W.W.; Structures of the Human Gtpase Mmaa and Vitamin B12-Dependent Methylmalonyl-Coa Mutase and Insight Into Their Complex Formation.; J.Biol.Chem., 285:38204-, 2010; PubMed: 20876572; DOI: 10.1074/JBC.M110.177717

実験手法

X-RAY DIFFRACTION (1.95 Å)