2WWY

Structure of human RECQ-like helicase in complex with a DNA substrate

Summary for 2WWY

• Entry DOI: 10.2210/pdb2wwy/pdb
• Related: 2V1X
• Descriptor: ATP-DEPENDENT DNA HELICASE Q1, DNA OLIGO (27BP), 5'-D(*DA DG DC DG DT DC DG DA DG DA DT DC DCP)-3', ... (7 entities in total)
• Functional Keywords: hydrolase-dna complex, nuclear protein, hydrolase, dna strand annealing, dna-binding, hydrolase/dna
• Biological source: HOMO SAPIENS (HUMAN); More
• Total number of polymer chains: 8
• Total formula weight: 176203.35

Authors

Pike, A.C.W.,Zhang, Y.,Schnecke, C.,Chaikuad, A.,Krojer, T.,Cooper, C.D.O.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Gileadi, O. (deposition date: 2009-10-30, release date: 2009-12-29, Last modification date: 2023-12-20)

• Primary citation: Pike, A.C.W.,Zhang, Y.,Schnecke, C.,Chaikuad, A.,Krojer, T.,Cooper, C.D.O.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.,Bountra, C.,Gileadi, O.; Recq1 Helicase-Driven DNA Unwinding, Annealing, and Branch Migration: Insights from DNA Complex Structures; Proc.Natl.Acad.Sci.USA, 112:4286-, 2015; PubMed: 25831490; DOI: 10.1073/PNAS.1417594112

Experimental method

X-RAY DIFFRACTION (2.9 Å)