2WO3

Crystal Structure of the EphA4-ephrinA2 complex

Summary for 2WO3

• Entry DOI: 10.2210/pdb2wo3/pdb
• Related: 2WO1 2WO2
• Descriptor: EPHRIN TYPE-A RECEPTOR, EPHRIN-A2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: transferase-signaling protein complex, efn, eph, epha4, kinase, ephrin, complex, membrane, cell surface receptor, tyrosine-protein kinase, glycoprotein, ephrina2, transferase/signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 39956.70

Authors

Bowden, T.A.,Aricescu, A.R.,Nettleship, J.E.,Siebold, C.,Rahman-Huq, N.,Owens, R.J.,Stuart, D.I.,Jones, E.Y. (deposition date: 2009-07-21, release date: 2009-10-27, Last modification date: 2023-12-20)

• Primary citation: Bowden, T.A.,Aricescu, A.R.,Nettleship, J.E.,Siebold, C.,Rahman-Huq, N.,Owens, R.J.,Stuart, D.I.,Jones, E.Y.; Structural Plasticity of Eph-Receptor A4 Facilitates Cross-Class Ephrin Signalling; Structure, 17:1386-, 2009; PubMed: 19836338; DOI: 10.1016/J.STR.2009.07.018

Experimental method

X-RAY DIFFRACTION (2.35 Å)