2WNG
complete extracellular structure of human signal regulatory protein (SIRP) alpha
Summary for 2WNG
Entry DOI | 10.2210/pdb2wng/pdb |
Related | 2JJS 2JJT 2UV3 |
Descriptor | TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total) |
Functional Keywords | signal regulatory protein alpha, immunoglobulin superfamily, phosphoprotein, disulfide bond, paired receptor, alternative splicing, immunoglobulin domain, sirp, cd47, sirpa, membrane, sh3-binding, polymorphism, glycoprotein, transmembrane, cell adhesion |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 36425.54 |
Authors | Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N. (deposition date: 2009-07-09, release date: 2009-07-21, Last modification date: 2023-12-13) |
Primary citation | Hatherley, D.,Graham, S.C.,Harlos, K.,Stuart, D.I.,Barclay, A.N. Structure of Signal-Regulatory Protein Alpha: A Link to Antigen Receptor Evolution. J.Biol.Chem., 284:26613-, 2009 Cited by PubMed: 19628875DOI: 10.1074/JBC.M109.017566 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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