2WDT

Crystal structure of Plasmodium falciparum UCHL3 in complex with the suicide inhibitor UbVME

Summary for 2WDT

Entry DOI	10.2210/pdb2wdt/pdb
Related	1C3T 1D3Z 1F9J 1FXT 1G6J 1GJZ 1NBF 1OGW 1Q5W 1S1Q 1SIF 1TBE 1UBI 1UBQ 1XD3 1XQQ 1YX5 1YX6 1ZGU 2AYO 2BGF 2G45 2GBJ 2GBK 2GBM 2GBN 2J7Q 2JF5 2W9N
Descriptor	UBIQUITIN CARBOXYL-TERMINAL HYDROLASE L3, UBIQUITIN, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	hydrolase-protein binding complex, enzyme-ligand complex, ubiquitin isopeptidase, uch-l superfamily, cystein proteinase, peptidase_c12, hydrolase, hydrolase/protein binding
Biological source	PLASMODIUM FALCIPARUM (MALARIA PARASITE) More
Total number of polymer chains	4
Total formula weight	71169.37
Authors	Weihofen, W.A.,Artavanis-Tsakonas, K.,Gaudet, R.,Ploegh, H.L. (deposition date: 2009-03-26, release date: 2009-12-29, Last modification date: 2023-12-13)
Primary citation	Artavanis-Tsakonas, K.,Weihofen, W.A.,Antos, J.M.,Coleman, B.I.,Comeaux, C.A.,Duraisingh, M.T.,Gaudet, R.,Ploegh, H.L. Characterization and Structural Studies of the Plasmodium Falciparum Ubiquitin and Nedd8 Hydrolase Uchl3. J.Biol.Chem., 285:6857-, 2010 Cited by PubMed: 20042598 DOI: 10.1074/JBC.M109.072405 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation