2VKZ

Structure of the cerulenin-inhibited fungal fatty acid synthase type I multienzyme complex

Summary for 2VKZ

• Entry DOI: 10.2210/pdb2vkz/pdb
• Related: 2UV8
• Descriptor: FATTY ACID SYNTHASE SUBUNIT ALPHA, FATTY ACID SYNTHASE SUBUNIT BETA, (2S, 3R)-3-HYDROXY-4-OXO-7,10-TRANS,TRANS-DODECADIENAMIDE, ... (4 entities in total)
• Functional Keywords: transferase, phosphorylation, phosphopantetheine, fatty acid synthase, multifunctional enzyme, oxidoreductase, lipid synthesis, fas, nad, nadp, lyase, cerulenin, hydrolase, fatty acid biosynthesis
• Biological source: SACCHAROMYCES CEREVISIAE (BAKER'S YEAST); More
• Total number of polymer chains: 6
• Total formula weight: 1310419.27

Authors

Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M. (deposition date: 2008-01-07, release date: 2008-08-12, Last modification date: 2017-06-21)

• Primary citation: Johansson, P.,Wiltschi, B.,Kumari, P.,Kessler, B.,Vonrhein, C.,Vonck, J.,Oesterhelt, D.,Grininger, M.; Inhibition of the Fungal Fatty Acid Synthase Type I Multienzyme Complex.; Proc.Natl.Acad.Sci.USA, 105:12803-, 2008; PubMed: 18725634; DOI: 10.1073/PNAS.0805827105

Experimental method

X-RAY DIFFRACTION (4 Å)