2VFJ

Structure of the A20 Ovarian Tumour (OTU) domain

Summary for 2VFJ

Entry DOI	10.2210/pdb2vfj/pdb
Descriptor	TUMOR NECROSIS FACTOR, SULFATE ION, MAGNESIUM ION (3 entities in total)
Functional Keywords	phosphorylation, cysteine protease, metal-binding, ovarian tumour, thiol protease, dna-binding, polymorphism, lys63-linked, hydrolase, cytoplasm, ubiquitin, zinc-finger, deubiquitinating enzyme, cytokine signalling, ubl conjugation pathway, otu, zinc, nf-kb, nucleus, protease, apoptosis
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: P21580
Total number of polymer chains	4
Total formula weight	172822.48
Authors	Komander, D.,Barford, D. (deposition date: 2007-11-04, release date: 2007-12-04, Last modification date: 2011-07-13)
Primary citation	Komander, D.,Barford, D. Structure of the A20 Otu Domain and Mechanistic Insights Into Deubiquitination Biochem.J., 409:77-, 2008 Cited by PubMed: 17961127 DOI: 10.1042/BJ20071399 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation