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2UXN

Structural Basis of Histone Demethylation by LSD1 Revealed by Suicide Inactivation

Summary for 2UXN
Entry DOI10.2210/pdb2uxn/pdb
Related2B2T 2B2U 2B2V 2B2W 2C1J 2C1N 2COM 2CV5 2H94 2IW5 2UXX
DescriptorLYSINE-SPECIFIC HISTONE DEMETHYLASE 1, REST COREPRESSOR 1, HISTONE H3.1, ... (7 entities in total)
Functional Keywordsoxidoreductase-transcription regulator complex, oxidoreductase-repressor complex, histone demethylase, fad, lsd1, corest, repressor, transcription regulation, host-virus interaction, chromatin demethylation, nuclear protein, phosphorylation, chromatin regulator, nucleosomes, transcription, oxidoreductase, oxidoreductase/transcription regulator
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationNucleus: O60341 Q9UKL0 P68431
Total number of polymer chains3
Total formula weight103819.83
Authors
Yang, M.,Culhane, J.C.,Szewczuk, L.M.,Gocke, C.B.,Brautigam, C.A.,Tomchick, D.R.,Machius, M.,Cole, P.A.,Yu, H. (deposition date: 2007-03-28, release date: 2007-05-29, Last modification date: 2011-07-13)
Primary citationYang, M.,Culhane, J.C.,Szewczuk, L.M.,Gocke, C.B.,Brautigam, C.A.,Tomchick, D.R.,Machius, M.,Cole, P.A.,Yu, H.
Structural Basis of Histone Demethylation by Lsd1 Revealed by Suicide Inactivation.
Nat.Struct.Mol.Biol., 14:535-, 2007
Cited by
PubMed: 17529991
DOI: 10.1038/NSMB1255
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.72 Å)
Structure validation

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