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2R0W

PFA2 FAB complexed with Abeta1-8

Summary for 2R0W
Entry DOI10.2210/pdb2r0w/pdb
Related2IPT 2IPU 2IQ9 2IQA 2R0W 2R0Z
DescriptorIgG2a Fab fragment light chain, IgG2a Fab fragment heavy chain, Fd portion, Amyloid beta peptide fragment, ... (5 entities in total)
Functional Keywordsimmunoglobulin; alzheimer disease; amyloid, immune system
Biological sourceMus musculus (house mouse)
More
Cellular locationMembrane; Single-pass type I membrane protein: P05067
Total number of polymer chains3
Total formula weight49224.90
Authors
Gardberg, A.S.,Dealwis, C. (deposition date: 2007-08-21, release date: 2007-10-16, Last modification date: 2017-10-25)
Primary citationGardberg, A.S.,Dice, L.T.,Ou, S.,Rich, R.L.,Helmbrecht, E.,Ko, J.,Wetzel, R.,Myszka, D.G.,Patterson, P.H.,Dealwis, C.
Molecular basis for passive immunotherapy of Alzheimer's disease
Proc.Natl.Acad.Sci.Usa, 104:15659-15664, 2007
Cited by
PubMed: 17895381
DOI: 10.1073/pnas.0705888104
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.503 Å)
Structure validation

217705

數據於2024-03-27公開中

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