2QNA

Crystal structure of human Importin-beta (127-876) in complex with the IBB-domain of Snurportin1 (1-65)

Summary for 2QNA

Entry DOI	10.2210/pdb2qna/pdb
Descriptor	Importin subunit beta-1, Snurportin-1, SULFATE ION, ... (4 entities in total)
Functional Keywords	nuclear transport, import of spliceosomal subunits, protein-protein interaction, heat-repeat protein, host-virus interaction, nucleus, protein transport, rna-binding, transport protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm : Q14974 Nucleus : O95149
Total number of polymer chains	2
Total formula weight	92437.16
Authors	Wohlwend, D.,Strasser, A.,Dickmanns, A.,Ficner, R. (deposition date: 2007-07-18, release date: 2008-04-08, Last modification date: 2024-02-21)
Primary citation	Wohlwend, D.,Strasser, A.,Dickmanns, A.,Ficner, R. Structural basis for RanGTP independent entry of spliceosomal U snRNPs into the nucleus. J.Mol.Biol., 374:1129-1138, 2007 Cited by PubMed: 18028944 DOI: 10.1016/j.jmb.2007.09.065 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation