2QBX
EphB2/SNEW Antagonistic Peptide Complex
Summary for 2QBX
Entry DOI | 10.2210/pdb2qbx/pdb |
Related | 1KGY 1NUK 2BBA |
Descriptor | Ephrin type-B receptor 2, antagonistic peptide, SULFATE ION, ... (4 entities in total) |
Functional Keywords | receptor tyrosine kinase, bi-directional signaling, tumorigenesis, angiogenesis, signaling protein, structural genomics, psi-2, protein structure initiative, accelerated technologies center for gene to 3d structure, atcg3d |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P29323 |
Total number of polymer chains | 4 |
Total formula weight | 51495.56 |
Authors | Chrencik, J.E.,Brooun, A.,Recht, M.I.,Nicola, G.,Pasquale, E.B.,Kuhn, P.,Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) (deposition date: 2007-06-18, release date: 2007-11-06, Last modification date: 2023-08-30) |
Primary citation | Chrencik, J.E.,Brooun, A.,Recht, M.I.,Nicola, G.,Davis, L.K.,Abagyan, R.,Widmer, H.,Pasquale, E.B.,Kuhn, P. Three-dimensional structure of the EphB2 receptor in complex with an antagonistic peptide reveals a novel mode of inhibition. J.Biol.Chem., 282:36505-36513, 2007 Cited by PubMed: 17897949DOI: 10.1074/jbc.M706340200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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