2Q3K

Crystal Structure of Lysine Sulfonamide Inhibitor Reveals the Displacement of the Conserved Flap Water Molecule in HIV-1 Protease

2Q3K の概要

• エントリーDOI: 10.2210/pdb2q3k/pdb
• 分子名称: Protease, PHOSPHATE ION, ACETATE ION, ... (5 entities in total)
• 機能のキーワード: drug design, hiv-1 protease, protease inhibitors, viral protein
• 由来する生物種: Human immunodeficiency virus 1
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 22637.47

構造登録者

Schiffer, C.A.,Nalam, M.N.L. (登録日: 2007-05-30, 公開日: 2007-08-21, 最終更新日: 2023-08-30)

• 主引用文献: Nalam, M.N.,Peeters, A.,Jonckers, T.H.,Dierynck, I.,Schiffer, C.A.; Crystal structure of lysine sulfonamide inhibitor reveals the displacement of the conserved flap water molecule in human immunodeficiency virus type 1 protease.; J.Virol., 81:9512-9518, 2007; PubMed: 17596316; DOI: 10.1128/JVI.00799-07

実験手法

X-RAY DIFFRACTION (2 Å)