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2PZE

Minimal human CFTR first nucleotide binding domain as a head-to-tail dimer

Summary for 2PZE
Entry DOI10.2210/pdb2pze/pdb
Related1L2T 1Q12 1R0Z 1R10 1XEF 1XMI 1XMJ 2BB0 2BBS 2BBT 2HYD 2IXE 2PZF 2PZG
DescriptorCystic fibrosis transmembrane conductance regulator, MAGNESIUM ION, ADENOSINE-5'-TRIPHOSPHATE, ... (4 entities in total)
Functional Keywordsnbd, abc transporter, cftr, hydrolase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains2
Total formula weight52113.79
Authors
Atwell, S.,Conners, K.,Emtage, S.,Gheyi, T.,Glenn, N.R.,Hendle, J.,Lewis, H.A.,Lu, F.,Rodgers, L.A.,Romero, R.,Sauder, J.M.,Smith, D.,Tien, H.,Wasserman, S.R.,Zhao, X. (deposition date: 2007-05-17, release date: 2007-10-09, Last modification date: 2023-08-30)
Primary citationAtwell, S.,Brouillette, C.G.,Conners, K.,Emtage, S.,Gheyi, T.,Guggino, W.B.,Hendle, J.,Hunt, J.F.,Lewis, H.A.,Lu, F.,Protasevich, I.I.,Rodgers, L.A.,Romero, R.,Wasserman, S.R.,Weber, P.C.,Wetmore, D.,Zhang, F.F.,Zhao, X.
Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant.
Protein Eng.Des.Sel., 23:375-384, 2010
Cited by
PubMed: 20150177
DOI: 10.1093/protein/gzq004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.7 Å)
Structure validation

217705

数据于2024-03-27公开中

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