2PRG

LIGAND-BINDING DOMAIN OF THE HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA

Summary for 2PRG

Entry DOI	10.2210/pdb2prg/pdb
Descriptor	PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA, NUCLEAR RECEPTOR COACTIVATOR SRC-1, 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), ... (4 entities in total)
Functional Keywords	complex (thiazolidinedione-receptor), ligand-binding domain, nuclear receptor, apo, transcription factor, orphan receptor, complex (thiazolidinedione-receptor) complex, complex (thiazolidinedione/receptor)
Biological source	Homo sapiens (human) More
Total number of polymer chains	3
Total formula weight	72105.12
Authors	Nolte, R.T.,Wisely, G.B.,Milburn, M.V. (deposition date: 1998-08-14, release date: 1999-07-19, Last modification date: 2023-08-09)
Primary citation	Nolte, R.T.,Wisely, G.B.,Westin, S.,Cobb, J.E.,Lambert, M.H.,Kurokawa, R.,Rosenfeld, M.G.,Willson, T.M.,Glass, C.K.,Milburn, M.V. Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma. Nature, 395:137-143, 1998 Cited by PubMed: 9744270 DOI: 10.1038/25931 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation