2PA1

Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin

Summary for 2PA1

DescriptorPDZ and LIM domain protein 2, CHLORIDE ION (3 entities in total)
Functional Keywordspdz domain, structural genomics, structural genomics consortium, sgc, metal binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm . Isoform 1: Cytoplasm, cytoskeleton. Isoform 2: Cytoplasm, cytoskeleton. Isoform 3: Nucleus Q96JY6
Total number of polymer chains1
Total molecular weight9419.63
Authors
Primary citation
Uppenberg, J.,Shrestha, L.,Elkins, J.,Burgess-Brown, N.,Salah, E.,Bunkoczi, G.,Papagrigoriou, E.,Pike, A.C.W.,Turnbull, A.P.,Ugochukwu, E.,Umeano, C.,von Delft, F.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.,Sundstrom, M.,Doyle, D.A.
Structure of the PDZ domain of human PDLIM2 bound to a C-terminal extension from human beta-tropomyosin.
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2472001.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report