2P6A
The structure of the Activin:Follistatin 315 complex
Summary for 2P6A
| Entry DOI | 10.2210/pdb2p6a/pdb |
| Descriptor | Inhibin beta A chain, Follistatin, probable fragment of follistatin (3 entities in total) |
| Functional Keywords | follistatin, activin, inhibin, tgf-beta, signaling protein |
| Biological source | Homo sapiens (human) More |
| Cellular location | Secreted: P08476 P19883 |
| Total number of polymer chains | 5 |
| Total formula weight | 96305.28 |
| Authors | Lerch, T.F.,Shimasaki, S.,Woodruff, T.K.,Jardetzky, T.S. (deposition date: 2007-03-16, release date: 2007-04-03, Last modification date: 2023-08-30) |
| Primary citation | Lerch, T.F.,Shimasaki, S.,Woodruff, T.K.,Jardetzky, T.S. Structural and biophysical coupling of heparin and activin binding to follistatin isoform functions. J.Biol.Chem., 282:15930-15939, 2007 Cited by PubMed: 17409095DOI: 10.1074/jbc.M700737200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.4 Å) |
Structure validation
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