2P5B

The complex structure of JMJD2A and trimethylated H3K36 peptide

Summary for 2P5B

• Entry DOI: 10.2210/pdb2p5b/pdb
• Related: 2gp3 2gp5
• Descriptor: JmjC domain-containing histone demethylation protein 3A, Histone H3, ZINC ION, ... (7 entities in total)
• Functional Keywords: jmjd2a, jmjc domain, histone demethylase, metal binding protein
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: O75164; Nucleus (By similarity): P84239
• Total number of polymer chains: 4
• Total formula weight: 87211.48

Authors

Zhang, G.,Chen, Z.,Zang, J.,Hong, X.,Shi, Y. (deposition date: 2007-03-14, release date: 2007-06-12, Last modification date: 2013-11-27)

• Primary citation: Chen, Z.,Zang, J.,Kappler, J.,Hong, X.,Crawford, F.,Wang, Q.,Lan, F.,Jiang, C.,Whetstine, J.,Dai, S.,Hansen, K.,Shi, Y.,Zhang, G.; Structural basis of the recognition of a methylated histone tail by JMJD2A.; Proc.Natl.Acad.Sci.USA, 104:10818-10823, 2007; PubMed: 17567753; DOI: 10.1073/pnas.0704525104

Experimental method

X-RAY DIFFRACTION (1.99 Å)